The tumor microenvironment and how
one could reverse immunosupression. By studying tumor
and blood samples from patients treated with dendritic Cell
vaccines, both by immuno-histological, biochemical and by genomic
and transcriptome analyses, we try to develop novel prognostic and
predictive biomarkers. Also an in vitro 3D-Skin model is
built to systematically study tumor- microenvironment interactions
including immune cell migration.