Publications 2012

1. van Spriel AB, Cambi A. Binding and uptake of Candida albicans by human monocyte-derived dendritic cells. Methods Mol Biol, 2012. 845: 319-31.

2. Lamers E, te Riet J, Domanski M, Luttge R, Figdor CG, Gardeniers JG, Walboomers XF, Jansen JA. Dynamic cell adhesion and migration on nanoscale grooved substrates. European cells & materials, 2012. 23: 182-93; discussion 93-4.

3. Carroll-Portillo A, Surviladze Z, Cambi A, Lidke DS, Wilson BS. Mast cell synapses and exosomes: membrane contacts for information exchange. Frontiers in immunology, 2012. 3: 46.

4. Cruz LJ, Tacken PJ, Rueda F, Domingo JC, Albericio F, Figdor CG. Targeting nanoparticles to dendritic cells for immunotherapy. Methods in enzymology, 2012. 509: 143-63.

5. Rizzetto L, Buschow SI, Beltrame L, Figdor CG, Schierer S, Schuler G, Cavalieri D. The modular nature of dendritic cell responses to commensal and pathogenic fungi. PLoS ONE, 2012. 7(8): e42430.

6. van Spriel AB, de Keijzer S, van der Schaaf A, Gartlan KH, Sofi M, Light A, Linssen PC, Boezeman JB, Zuidscherwoude M, Reinieren-Beeren I, Cambi A, Mackay F, Tarlinton DM, Figdor CG, Wright MD. The Tetraspanin CD37 Orchestrates the alpha4beta1 Integrin-Akt Signaling Axis and Supports Long-Lived Plasma Cell Survival. Sci Signal, 2012. 5(250): ra82.

7. Prinsen H, de Vries IJ, Torensma R, Pots JM, Mulder SF, van Herpen CM, Elving LD, Bleijenberg G, Stelma FF, van Laarhoven HW. Humoral and cellular immune responses after influenza vaccination in patients with chronic fatigue syndrome. BMC Immunol, 2012. 13: 71.

8. Hontelez S, Sanecka A, Netea MG, van Spriel AB, Adema GJ. Molecular view on PRR cross-talk in antifungal immunity. Cellular microbiology, 2012. 14(4): 467-74.

9. Baron F, Suciu S, Amadori S, Muus P, Zwierzina H, Denzlinger C, Delforge M, Thyss A, Selleslag D, Indrak K, Ossenkoppele G, de Witte T. Value of infliximab (Remicade(R)) in patients with low-risk myelodysplastic syndrome: final results of a randomized phase II trial (EORTC trial 06023) of the EORTC Leukemia Group. Haematologica, 2012. 97(4): 529-33.

10. Schulte BM, Lanke KH, Piganelli JD, Kers-Rebel ED, Bottino R, Trucco M, Huijbens RJ, Radstake TR, Engelse MA, de Koning EJ, Galama JM, Adema GJ, van Kuppeveld FJ. Cytokine and chemokine production by human pancreatic islets upon enterovirus infection. Diabetes, 2012. 61(8): 2030-6.

11. Tacken PJ, Ter Huurne M, Torensma R, Figdor CG. Antibodies and carbohydrate ligands binding to DC-SIGN differentially modulate receptor trafficking. Eur J Immunol, 2012. 42(8): 1989-98.

12. Aarntzen EH, Srinivas M, Punt CJ, Figdor CG, Oyen WJ, de Vries IJ. Insight into the dynamics, localization and magnitude of antigen-specific immune responses by [(18)F]FLT PET imaging. Oncoimmunology, 2012. 1(5): 744-5.

13. Shekhar S, Cambi A, Figdor CG, Subramaniam V, Kanger JS. A method for spatially resolved local intracellular mechanochemical sensing and organelle manipulation. Biophys J, 2012. 103(3): 395-404.

14. Srinivas M, Boehm-Sturm P, Figdor CG, de Vries IJ, Hoehn M. Labeling cells for in vivo tracking using (19)F MRI. Biomaterials, 2012. 33(34): 8830-40.

15. Aarntzen EH, Srinivas M, Walczak P, Janowski M, Heerschap A, de Vries IJ, Figdor CG, Bulte JW, Oyen WJ. In vivo tracking techniques for cellular regeneration, replacement, and redirection. J Nucl Med, 2012. 53(12): 1825-8.

16. Ansems M, Karthaus N, Hontelez S, Aalders T, Looman MW, Verhaegh GW, Schalken JA, Adema GJ. DC-SCRIPT: AR and VDR regulator lost upon transformation of prostate epithelial cells. The Prostate, 2012. 72(16): 1708-17.

17. Aarntzen EH, Bol K, Schreibelt G, Jacobs JF, Lesterhuis WJ, Van Rossum MM, Adema GJ, Figdor CG, Punt CJ, De Vries IJ. Skin-test infiltrating lymphocytes early predict clinical outcome of dendritic cell-based vaccination in metastatic melanoma. Cancer Res, 2012. 72(23): 6102-10.

18. Martino R, de Wreede L, Fiocco M, van Biezen A, von dem Borne PA, Hamladji RM, Volin L, Bornhauser M, Robin M, Rocha V, de Witte T, Kroger N, Mohty M. Comparison of conditioning regimens of various intensities for allogeneic hematopoietic SCT using HLA-identical sibling donors in AML and MDS with . Bone Marrow Transplant, 2012.

19. Blijlevens N, de Chateau M, Krivan G, Rabitsch W, Szomor A, Pytlik R, Lissmats A, Johnsen HE, de Witte T, Einsele H, Ruutu T, Niederwieser D. In a high-dose melphalan setting, palifermin compared with placebo had no effect on oral mucositis or related patient's burden. Bone Marrow Transplant, 2012.

20. Torensma R, Prins HJ, Schrama E, Verwiel ET, Martens AC, Roelofs H, Jansen BJ. The Impact of Cell Source, Culture Methodology, Culture Location, and Individual Donors on Gene Expression Profiles of Bone Marrow-Derived and Adipose-Derived Stromal Cells. Stem Cells Dev, 2012.

21. Joniau S, Abrahamsson PA, Bellmunt J, Figdor C, Hamdy F, Verhagen P, Vogelzang NJ, Wirth M, Van Poppel H, Osanto S. Current vaccination strategies for prostate cancer. European urology, 2012. 61(2): 290-306.

22. Kroesen M, Lindau D, Hoogerbrugge P, Adema GJ. Immunocombination therapy for high-risk neuroblastoma. Immunotherapy, 2012. 4(2): 163-74.

23. Grefte S, Kuijpers MA, Kuijpers-Jagtman AM, Torensma R, Von den Hoff JW. Myogenic capacity of muscle progenitor cells from head and limb muscles. Eur J Oral Sci, 2012. 120(1): 38-45.

24. Sanecka A, Ansems M, van Hout-Kuijer MA, Looman MW, Prosser AC, Welten S, Gilissen C, Sama IE, Huynen MA, Veltman JA, Jansen BJ, Eleveld-Trancikova D, Adema GJ. Analysis of genes regulated by the transcription factor LUMAN identifies ApoA4 as a target gene in dendritic cells. Molecular immunology, 2012. 50(1-2): 66-73.

25. Tel J, van der Leun AM, Figdor CG, Torensma R, de Vries IJ. Harnessing human plasmacytoid dendritic cells as professional APCs. Cancer Immunol Immunother, 2012.

26. Buschow SI, Lasonder E, Szklarczyk R, Oud MM, de Vries IJ, Figdor CG. Unraveling the human dendritic cell phagosome proteome by organellar enrichment ranking. Journal of proteomics, 2012. 75(5): 1547-62.

27. Jacobs JF, Nierkens S, Figdor CG, de Vries IJ, Adema GJ. Regulatory T cells in melanoma: the final hurdle towards effective immunotherapy?. The lancet oncology, 2012. 13(1): e32-42.

28. Verstappen J, van Rheden RE, Katsaros C, Torensma R, Von den Hoff JW. Preferential recruitment of bone marrow-derived cells to rat palatal wounds but not to skin wounds. Archives of oral biology, 2012. 57(1): 102-8.

29. den Brok MH, Nierkens S, Wagenaars JA, Ruers TJ, Schrier CC, Rijke EO, Adema GJ. Saponin-based adjuvants create a highly effective anti-tumor vaccine when combined with in situ tumor destruction. Vaccine, 2012. 30(4): 737-44.

30. Cambi A, Lidke DS. Nanoscale membrane organization: where biochemistry meets advanced microscopy. ACS chemical biology, 2012. 7(1): 139-49.

31. Schonland SO, Dreger P, de Witte T, Hegenbart U. Current status of hematopoietic cell transplantation in the treatment of systemic amyloid light-chain amyloidosis. Bone Marrow Transplant, 2012. 47(7): 895-905.

32. Tel J, Hato SV, Torensma R, Buschow SI, Figdor CG, Lesterhuis WJ, de Vries IJ. The chemotherapeutic drug oxaliplatin differentially affects blood DC function dependent on environmental cues. Cancer Immunol Immunother, 2012. 61(7): 1101-11.

33. Westers TM, Ireland R, Kern W, Alhan C, Balleisen JS, Bettelheim P, Burbury K, Cullen M, Cutler JA, Della Porta MG, Drager AM, Feuillard J, Font P, Germing U, Haase D, Johansson U, Kordasti S, Loken MR, Malcovati L, Te Marvelde JG, Matarraz S, Milne T, Moshaver B, Mufti GJ, Ogata K, Orfao A, Porwit A, Psarra K, Richards SJ, Subira D, Tindell V, Vallespi T, Valent P, van der Velden VH, de Witte TM, Wells DA, Zettl F, Bene MC, van de Loosdrecht AA. Standardization of flow cytometry in myelodysplastic syndromes: a report from an international consortium and the European LeukemiaNet Working Group. Leukemia, 2012. 26(7): 1730-41.

34. Hontelez S, Ansems M, Karthaus N, Zuidscherwoude M, Looman MW, Triantis V, Adema GJ. Dendritic cell-specific transcript: dendritic cell marker and regulator of TLR-induced cytokine production. J Immunol, 2012. 189(1): 138-45.

35. Garderet L, Iacobelli S, Moreau P, Dib M, Lafon I, Niederwieser D, Masszi T, Fontan J, Michallet M, Gratwohl A, Milone G, Doyen C, Pegourie B, Hajek R, Casassus P, Kolb B, Chaleteix C, Hertenstein B, Onida F, Ludwig H, Ketterer N, Koenecke C, van Os M, Mohty M, Cakana A, Gorin NC, de Witte T, Harousseau JL, Morris C, Gahrton G. Superiority of the Triple Combination of Bortezomib-Thalidomide-Dexamethasone Over the Dual Combination of Thalidomide-Dexamethasone in Patients With Multiple Myeloma Progressing or Relapsing After Autologous Transplantation: The MMVAR/IFM 2005-04 Randomized Phase III Trial From the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation. J Clin Oncol, 2012. 30(20): 2475-82.

36. Kroger N, Zabelina T, de Wreede L, Berger J, Alchalby H, van Biezen A, Milpied N, Volin L, Mohty M, Leblond V, Blaise D, Finke J, Schaap N, Robin M, de Witte T. Allogeneic stem cell transplantation for older advanced MDS patients: improved survival with young unrelated donor in comparison with HLA-identical siblings. Leukemia, 2012.

37. Andersen PK, Geskus RB, de Witte T, Putter H. Competing risks in epidemiology: possibilities and pitfalls. International journal of epidemiology, 2012. 41(3): 861-70.

38. Cruz LJ, Tacken PJ, Pots JM, Torensma R, Buschow SI, Figdor CG. Comparison of antibodies and carbohydrates to target vaccines to human dendritic cells via DC-SIGN. Biomaterials, 2012. 33(16): 4229-39.

39. Fransen JH, Berden JH, Koeter CM, Adema GJ, Van Der Vlag J, Hilbrands LB. Effect of administration of apoptotic blebs on disease development in lupus mice. Autoimmunity, 2012. 45(4): 290-7.

40. van den Dries K, van Helden SF, Riet J, Diez-Ahedo R, Manzo C, Oud MM, van Leeuwen FN, Brock R, Garcia-Parajo MF, Cambi A, Figdor CG. Geometry sensing by dendritic cells dictates spatial organization and PGE(2)-induced dissolution of podosomes. Cell Mol Life Sci, 2012. 69(11): 1889-901.

41. Hengeveld M, Suciu S, Karrasch M, Specchia G, Marie JP, Muus P, Petti MC, Rotoli B, Amadori S, Fioritoni G, Leoni P, Morra E, Thaler J, Resegotti L, Fazi P, Vignetti M, Mandelli F, Zittoun R, de Witte T. Intensive consolidation therapy compared with standard consolidation and maintenance therapy for adults with acute myeloid leukaemia aged between 46 and 60 years: final results of the randomized phase III study (AML 8B) of the European Organization for Research and Treatment of Cancer (EORTC) and the Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA) Leukemia Cooperative Groups. Annals of hematology, 2012. 91(6): 825-35.

42. van Bijnen ST, van Rijn RS, Koljenovic S, Te Boekhorst P, de Witte T, Muus P. Possible high risk of thrombotic events in patients with paroxysmal nocturnal haemoglobinuria after discontinuation of eculizumab. British journal of haematology, 2012. 157(6): 762-3.

43. Cwynarski K, van Biezen A, de Wreede L, Stilgenbauer S, Bunjes D, Metzner B, Koza V, Mohty M, Remes K, Russell N, Nagler A, Scholten M, de Witte T, Sureda A, Dreger P. Autologous and allogeneic stem-cell transplantation for transformed chronic lymphocytic leukemia (Richter's syndrome): A retrospective analysis from the chronic lymphocytic leukemia subcommittee of the chronic leukemia working party and lymphoma working party of the European Group for Blood and Marrow Transplantation. J Clin Oncol, 2012. 30(18): 2211-7.

44. Moghadasali R, Mutsaers HA, Azarnia M, Aghdami N, Baharvand H, Torensma R, Wilmer MJ, Masereeuw R. Mesenchymal stem cell-conditioned medium accelerates regeneration of human renal proximal tubule epithelial cells after gentamicin toxicity. Exp Toxicol Pathol, 2012.

45. Schreibelt G, Klinkenberg LJ, Cruz LJ, Tacken PJ, Tel J, Kreutz M, Adema GJ, Brown GD, Figdor CG, de Vries IJ. The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cells. Blood, 2012. 119(10): 2284-92.

46. Bakker GJ, Eich C, Torreno-Pina JA, Diez-Ahedo R, Perez-Samper G, van Zanten TS, Figdor CG, Cambi A, Garcia-Parajo MF. Lateral mobility of individual integrin nanoclusters orchestrates the onset for leukocyte adhesion. Proc Natl Acad Sci U S A, 2012. 109(13): 4869-74.

47. Moulin V, Morgan ME, Eleveld-Trancikova D, Haanen JB, Wielders E, Looman MW, Janssen RA, Figdor CG, Jansen BJ, Adema GJ. Targeting dendritic cells with antigen via dendritic cell-associated promoters. Cancer gene therapy, 2012. 19(5): 303-11.

48. Wiktor-Jedrzejczak W, Dearden C, de Wreede L, van Biezen A, Brinch L, Leblond V, Brune M, Volin L, Kazmi M, Nagler A, Schetelig J, de Witte T, Dreger P. Hematopoietic stem cell transplantation in T-prolymphocytic leukemia: a retrospective study from the European Group for Blood and Marrow Transplantation and the Royal Marsden Consortium. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 2012. 26(5): 972-6.

49. Ruutu T, van Biezen A, Hertenstein B, Henseler A, Garderet L, Passweg J, Mohty M, Sureda A, Niederwieser D, Gratwohl A, de Witte T. Prophylaxis and treatment of GVHD after allogeneic haematopoietic SCT: a survey of centre strategies by the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant, 2012. 47(11): 1459-64.

50. Aarntzen EH, de Vries IJ, Goertz JH, Beldhuis-Valkis M, Brouwers HM, van de Rakt MW, van der Molen RG, Punt CJ, Adema GJ, Tacken PJ, Joosten I, Jacobs JF. Humoral anti-KLH responses in cancer patients treated with dendritic cell-based immunotherapy are dictated by different vaccination parameters. Cancer Immunol Immunother, 2012. 61(11): 2003-11.

51. Tel J, Smits EL, Anguille S, Joshi RN, Figdor CG, de Vries IJ. Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities. Blood, 2012. 120(19): 3936-44.

52. Manzo C, Torreno-Pina JA, Joosten B, Reinieren-Beeren I, Gualda EJ, Loza-Alvarez P, Figdor CG, Garcia-Parajo MF, Cambi A. The neck region of the C-type lectin DC-SIGN regulates its surface spatiotemporal organization and virus-binding capacity on antigen-presenting cells. J Biol Chem, 2012. 287(46): 38946-55.

53. Tang L, Bergevoet SM, Bakker-Verweij G, Harteveld CL, Giordano PC, Nijtmans L, de Witte T, Jansen JH, Raymakers RA, van der Reijden BA. Human mitochondrial ATP-binding cassette transporter ABCB10 is required for efficient red blood cell development. British journal of haematology, 2012. 157(1): 151-4.

54. Basak GW, de Wreede LC, van Biezen A, Wiktor-Jedrzejczak W, Halaburda K, Schmid C, Schaap N, Dazzi F, von dem Borne PA, Petersen E, Beelen D, Abayomi A, Volin L, Buzyn A, Gurman G, Bunjes D, Guglielmi C, Olavarria E, de Witte T. Donor lymphocyte infusions for the treatment of chronic myeloid leukemia relapse following peripheral blood or bone marrow stem cell transplantation. Bone Marrow Transplant, 2012.

55. Grefte S, Vullinghs S, Kuijpers-Jagtman AM, Torensma R, Von den Hoff JW. Matrigel, but not collagen I, maintains the differentiation capacity of muscle derived cells in vitro. Biomed Mater, 2012. 7(5): 055004.

56. Cruz LJ, Rueda F, Tacken P, Albericio F, Torensma R, Figdor CG. Enhancing immunogenicity and cross-reactivity of HIV-1 antigens by in vivo targeting to dendritic cells. Nanomedicine (Lond), 2012. 7(10): 1591-610.

57. Aarntzen EH, Schreibelt G, Bol K, Lesterhuis WJ, Croockewit AJ, de Wilt JH, van Rossum MM, Blokx WA, Jacobs JF, Duiveman-de Boer T, Schuurhuis DH, Mus R, Thielemans K, de Vries IJ, Figdor CG, Punt CJ, Adema GJ. Vaccination with mRNA-Electroporated Dendritic Cells Induces Robust Tumor Antigen-Specific CD4+ and CD8+ T Cells Responses in Stage III and IV Melanoma Patients. Clin Cancer Res, 2012. 18(19): 5460-70.

58. Aarntzen EH, Srinivas M, Radu CG, Punt CJ, Boerman OC, Figdor CG, Oyen WJ, de Vries IJ. In vivo imaging of therapy-induced anti-cancer immune responses in humans. Cell Mol Life Sci, 2012.

59. van Gelder M, de Wreede LC, Schetelig J, van Biezen A, Volin L, Maertens J, Robin M, Petersen E, de Witte T, Kroger N. Monosomal karyotype predicts poor survival after allogeneic stem cell transplantation in chromosome 7 abnormal myelodysplastic syndrome and secondary acute myeloid leukemia. Leukemia, 2012.

60. Bonetto F, Srinivas M, Weigelin B, Cruz LJ, Heerschap A, Friedl P, Figdor CG, de Vries IJ. A large-scale (19) F MRI-based cell migration assay to optimize cell therapy. NMR in biomedicine, 2012. 25(9): 1095-103.

61. Karthaus N, Torensma R, Tel J. Deciphering the message broadcast by tumor-infiltrating dendritic cells. Am J Pathol, 2012. 181(3): 733-42.

62. Torensma R. Quantifying the efficacy of influenza vaccines. Lancet Infect Dis, 2012. 12(9): 656.

63. Vlachos C, Schulte BM, Magiatis P, Adema GJ, Gaitanis G. Malassezia-derived indoles activate the aryl hydrocarbon receptor and inhibit Toll-like receptor-induced maturation in monocyte-derived dendritic cells. The British journal of dermatology, 2012. 167(3): 496-505.

64. Zuidscherwoude M, van Spriel AB. The origin of IgE memory and plasma cells. Cell Mol Immunol, 2012. 9(5): 373-4.

65. Gilsanz A, Sanchez-Martin L, Gutierrez-Lopez MD, Ovalle S, Machado-Pineda Y, Reyes R, Swart GW, Figdor CG, Lafuente EM, Cabanas C. ALCAM/CD166 adhesive function is regulated by the tetraspanin CD9. Cell Mol Life Sci, 2012.