1. van Spriel AB, Cambi A. Binding and uptake of Candida albicans by human
monocyte-derived dendritic cells. Methods Mol
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2. Lamers E, te Riet J, Domanski M, Luttge R, Figdor CG,
Gardeniers JG, Walboomers XF, Jansen JA. Dynamic cell adhesion and migration on nanoscale
grooved substrates. European cells &
materials, 2012. 23: 182-93; discussion 93-4.
3. Carroll-Portillo A, Surviladze Z, Cambi A, Lidke DS, Wilson
BS. Mast cell synapses and exosomes: membrane contacts
for information exchange. Frontiers in
immunology, 2012. 3: 46.
4. Cruz LJ, Tacken PJ, Rueda F, Domingo JC, Albericio F, Figdor
CG. Targeting nanoparticles to dendritic cells for
immunotherapy. Methods in enzymology, 2012.
509: 143-63.
5. Rizzetto L, Buschow SI, Beltrame L, Figdor CG, Schierer S,
Schuler G, Cavalieri D. The modular nature of dendritic cell responses to
commensal and pathogenic fungi. PLoS ONE,
2012. 7(8): e42430.
6. van Spriel AB, de Keijzer S, van der Schaaf A, Gartlan KH,
Sofi M, Light A, Linssen PC, Boezeman JB, Zuidscherwoude M,
Reinieren-Beeren I, Cambi A, Mackay F, Tarlinton DM, Figdor CG,
Wright MD. The Tetraspanin CD37 Orchestrates the alpha4beta1
Integrin-Akt Signaling Axis and Supports Long-Lived Plasma Cell
Survival. Sci Signal, 2012. 5(250): ra82.
7. Prinsen H, de Vries IJ, Torensma R, Pots JM, Mulder SF, van
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Humoral and cellular immune responses after
influenza vaccination in patients with chronic fatigue
syndrome. BMC Immunol, 2012. 13: 71.
8. Hontelez S, Sanecka A, Netea MG, van Spriel AB, Adema GJ. Molecular view on PRR cross-talk in antifungal
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467-74.
9. Baron F, Suciu S, Amadori S, Muus P, Zwierzina H, Denzlinger
C, Delforge M, Thyss A, Selleslag D, Indrak K, Ossenkoppele G, de
Witte T. Value of infliximab (Remicade(R)) in patients with
low-risk myelodysplastic syndrome: final results of a randomized
phase II trial (EORTC trial 06023) of the EORTC Leukemia Group.
Haematologica, 2012. 97(4): 529-33.
10. Schulte BM, Lanke KH, Piganelli JD, Kers-Rebel ED, Bottino
R, Trucco M, Huijbens RJ, Radstake TR, Engelse MA, de Koning EJ,
Galama JM, Adema GJ, van Kuppeveld FJ. Cytokine and chemokine production by human
pancreatic islets upon enterovirus infection.
Diabetes, 2012. 61(8): 2030-6.
11. Tacken PJ, Ter Huurne M, Torensma R, Figdor CG. Antibodies and carbohydrate ligands binding to
DC-SIGN differentially modulate receptor trafficking.
Eur J Immunol, 2012. 42(8): 1989-98.
12. Aarntzen EH, Srinivas M, Punt CJ, Figdor CG, Oyen WJ, de
Vries IJ. Insight into the dynamics, localization and
magnitude of antigen-specific immune responses by [(18)F]FLT PET
imaging. Oncoimmunology, 2012. 1(5):
744-5.
13. Shekhar S, Cambi A, Figdor CG, Subramaniam V, Kanger JS. A method for spatially resolved local intracellular
mechanochemical sensing and organelle manipulation.
Biophys J, 2012. 103(3): 395-404.
14. Srinivas M, Boehm-Sturm P, Figdor CG, de Vries IJ, Hoehn M.
Labeling cells for in vivo tracking using (19)F
MRI. Biomaterials, 2012. 33(34): 8830-40.
15. Aarntzen EH, Srinivas M, Walczak P, Janowski M, Heerschap A,
de Vries IJ, Figdor CG, Bulte JW, Oyen WJ. In vivo tracking techniques for cellular
regeneration, replacement, and redirection. J Nucl
Med, 2012. 53(12): 1825-8.
16. Ansems M, Karthaus N, Hontelez S, Aalders T, Looman MW,
Verhaegh GW, Schalken JA, Adema GJ. DC-SCRIPT: AR and VDR regulator lost upon
transformation of prostate epithelial cells. The
Prostate, 2012. 72(16): 1708-17.
17. Aarntzen EH, Bol K, Schreibelt G, Jacobs JF, Lesterhuis WJ,
Van Rossum MM, Adema GJ, Figdor CG, Punt CJ, De Vries IJ. Skin-test infiltrating lymphocytes early predict
clinical outcome of dendritic cell-based vaccination in metastatic
melanoma. Cancer Res, 2012. 72(23):
6102-10.
18. Martino R, de Wreede L, Fiocco M, van Biezen A, von dem
Borne PA, Hamladji RM, Volin L, Bornhauser M, Robin M, Rocha V, de
Witte T, Kroger N, Mohty M. Comparison of conditioning regimens of various
intensities for allogeneic hematopoietic SCT using HLA-identical
sibling donors in AML and MDS with . Bone Marrow
Transplant, 2012.
19. Blijlevens N, de Chateau M, Krivan G, Rabitsch W, Szomor A,
Pytlik R, Lissmats A, Johnsen HE, de Witte T, Einsele H, Ruutu T,
Niederwieser D. In a high-dose melphalan setting, palifermin
compared with placebo had no effect on oral mucositis or related
patient's burden. Bone Marrow Transplant,
2012.
20. Torensma R, Prins HJ, Schrama E, Verwiel ET, Martens AC,
Roelofs H, Jansen BJ. The Impact of Cell Source, Culture Methodology,
Culture Location, and Individual Donors on Gene Expression Profiles
of Bone Marrow-Derived and Adipose-Derived Stromal Cells.
Stem Cells Dev, 2012.
21. Joniau S, Abrahamsson PA, Bellmunt J, Figdor C, Hamdy F,
Verhagen P, Vogelzang NJ, Wirth M, Van Poppel H, Osanto S. Current vaccination strategies for prostate
cancer. European urology, 2012. 61(2):
290-306.
22. Kroesen M, Lindau D, Hoogerbrugge P, Adema GJ. Immunocombination therapy for high-risk
neuroblastoma. Immunotherapy, 2012. 4(2):
163-74.
23. Grefte S, Kuijpers MA, Kuijpers-Jagtman AM, Torensma R, Von
den Hoff JW. Myogenic capacity of muscle progenitor cells from
head and limb muscles. Eur J Oral Sci, 2012.
120(1): 38-45.
24. Sanecka A, Ansems M, van Hout-Kuijer MA, Looman MW, Prosser
AC, Welten S, Gilissen C, Sama IE, Huynen MA, Veltman JA, Jansen
BJ, Eleveld-Trancikova D, Adema GJ. Analysis of genes regulated by the transcription
factor LUMAN identifies ApoA4 as a target gene in dendritic
cells. Molecular immunology, 2012. 50(1-2):
66-73.
25. Tel J, van der Leun AM, Figdor CG, Torensma R, de Vries IJ.
Harnessing human plasmacytoid dendritic cells as
professional APCs. Cancer Immunol Immunother,
2012.
26. Buschow SI, Lasonder E, Szklarczyk R, Oud MM, de Vries IJ,
Figdor CG. Unraveling the human dendritic cell phagosome
proteome by organellar enrichment ranking. Journal of
proteomics, 2012. 75(5): 1547-62.
27. Jacobs JF, Nierkens S, Figdor CG, de Vries IJ, Adema GJ. Regulatory T cells in melanoma: the final hurdle
towards effective immunotherapy?. The lancet
oncology, 2012. 13(1): e32-42.
28. Verstappen J, van Rheden RE, Katsaros C, Torensma R, Von den
Hoff JW. Preferential recruitment of bone marrow-derived
cells to rat palatal wounds but not to skin wounds.
Archives of oral biology, 2012. 57(1): 102-8.
29. den Brok MH, Nierkens S, Wagenaars JA, Ruers TJ, Schrier CC,
Rijke EO, Adema GJ. Saponin-based adjuvants create a highly effective
anti-tumor vaccine when combined with in situ tumor
destruction. Vaccine, 2012. 30(4): 737-44.
30. Cambi A, Lidke DS. Nanoscale membrane organization: where biochemistry
meets advanced microscopy. ACS chemical
biology, 2012. 7(1): 139-49.
31. Schonland SO, Dreger P, de Witte T, Hegenbart U. Current status of hematopoietic cell
transplantation in the treatment of systemic amyloid light-chain
amyloidosis. Bone Marrow Transplant, 2012.
47(7): 895-905.
32. Tel J, Hato SV, Torensma R, Buschow SI, Figdor CG,
Lesterhuis WJ, de Vries IJ. The chemotherapeutic drug oxaliplatin
differentially affects blood DC function dependent on environmental
cues. Cancer Immunol Immunother, 2012. 61(7):
1101-11.
33. Westers TM, Ireland R, Kern W, Alhan C, Balleisen JS,
Bettelheim P, Burbury K, Cullen M, Cutler JA, Della Porta MG,
Drager AM, Feuillard J, Font P, Germing U, Haase D, Johansson U,
Kordasti S, Loken MR, Malcovati L, Te Marvelde JG, Matarraz S,
Milne T, Moshaver B, Mufti GJ, Ogata K, Orfao A, Porwit A, Psarra
K, Richards SJ, Subira D, Tindell V, Vallespi T, Valent P, van der
Velden VH, de Witte TM, Wells DA, Zettl F, Bene MC, van de
Loosdrecht AA. Standardization of flow cytometry in
myelodysplastic syndromes: a report from an international
consortium and the European LeukemiaNet Working Group.
Leukemia, 2012. 26(7): 1730-41.
34. Hontelez S, Ansems M, Karthaus N, Zuidscherwoude M, Looman
MW, Triantis V, Adema GJ. Dendritic cell-specific transcript: dendritic cell
marker and regulator of TLR-induced cytokine production.
J Immunol, 2012. 189(1): 138-45.
35. Garderet L, Iacobelli S, Moreau P, Dib M, Lafon I,
Niederwieser D, Masszi T, Fontan J, Michallet M, Gratwohl A, Milone
G, Doyen C, Pegourie B, Hajek R, Casassus P, Kolb B, Chaleteix C,
Hertenstein B, Onida F, Ludwig H, Ketterer N, Koenecke C, van Os M,
Mohty M, Cakana A, Gorin NC, de Witte T, Harousseau JL, Morris C,
Gahrton G. Superiority of the Triple Combination of
Bortezomib-Thalidomide-Dexamethasone Over the Dual Combination of
Thalidomide-Dexamethasone in Patients With Multiple Myeloma
Progressing or Relapsing After Autologous Transplantation: The
MMVAR/IFM 2005-04 Randomized Phase III Trial From the Chronic
Leukemia Working Party of the European Group for Blood and Marrow
Transplantation. J Clin Oncol, 2012. 30(20):
2475-82.
36. Kroger N, Zabelina T, de Wreede L, Berger J, Alchalby H, van
Biezen A, Milpied N, Volin L, Mohty M, Leblond V, Blaise D, Finke
J, Schaap N, Robin M, de Witte T. Allogeneic stem cell transplantation for older
advanced MDS patients: improved survival with young unrelated donor
in comparison with HLA-identical siblings.
Leukemia, 2012.
37. Andersen PK, Geskus RB, de Witte T, Putter H. Competing risks in epidemiology: possibilities and
pitfalls. International journal of
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38. Cruz LJ, Tacken PJ, Pots JM, Torensma R, Buschow SI, Figdor
CG. Comparison of antibodies and carbohydrates to
target vaccines to human dendritic cells via DC-SIGN.
Biomaterials, 2012. 33(16): 4229-39.
39. Fransen JH, Berden JH, Koeter CM, Adema GJ, Van Der Vlag J,
Hilbrands LB. Effect of administration of apoptotic blebs on
disease development in lupus mice.
Autoimmunity, 2012. 45(4): 290-7.
40. van den Dries K, van Helden SF, Riet J, Diez-Ahedo R, Manzo
C, Oud MM, van Leeuwen FN, Brock R, Garcia-Parajo MF, Cambi A,
Figdor CG. Geometry sensing by dendritic cells dictates
spatial organization and PGE(2)-induced dissolution of
podosomes. Cell Mol Life Sci, 2012. 69(11):
1889-901.
41. Hengeveld M, Suciu S, Karrasch M, Specchia G, Marie JP, Muus
P, Petti MC, Rotoli B, Amadori S, Fioritoni G, Leoni P, Morra E,
Thaler J, Resegotti L, Fazi P, Vignetti M, Mandelli F, Zittoun R,
de Witte T. Intensive consolidation therapy compared with
standard consolidation and maintenance therapy for adults with
acute myeloid leukaemia aged between 46 and 60 years: final results
of the randomized phase III study (AML 8B) of the European
Organization for Research and Treatment of Cancer (EORTC) and the
Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA)
Leukemia Cooperative Groups. Annals of
hematology, 2012. 91(6): 825-35.
42. van Bijnen ST, van Rijn RS, Koljenovic S, Te Boekhorst P, de
Witte T, Muus P. Possible high risk of thrombotic events in patients
with paroxysmal nocturnal haemoglobinuria after discontinuation of
eculizumab. British journal of haematology,
2012. 157(6): 762-3.
43. Cwynarski K, van Biezen A, de Wreede L, Stilgenbauer S,
Bunjes D, Metzner B, Koza V, Mohty M, Remes K, Russell N, Nagler A,
Scholten M, de Witte T, Sureda A, Dreger P. Autologous and allogeneic stem-cell transplantation
for transformed chronic lymphocytic leukemia (Richter's syndrome):
A retrospective analysis from the chronic lymphocytic leukemia
subcommittee of the chronic leukemia working party and lymphoma
working party of the European Group for Blood and Marrow
Transplantation. J Clin Oncol, 2012. 30(18):
2211-7.
44. Moghadasali R, Mutsaers HA, Azarnia M, Aghdami N, Baharvand
H, Torensma R, Wilmer MJ, Masereeuw R. Mesenchymal stem cell-conditioned medium
accelerates regeneration of human renal proximal tubule epithelial
cells after gentamicin toxicity. Exp Toxicol
Pathol, 2012.
45. Schreibelt G, Klinkenberg LJ, Cruz LJ, Tacken PJ, Tel J,
Kreutz M, Adema GJ, Brown GD, Figdor CG, de Vries IJ. The C-type lectin receptor CLEC9A mediates antigen
uptake and (cross-)presentation by human blood BDCA3+ myeloid
dendritic cells. Blood, 2012. 119(10):
2284-92.
46. Bakker GJ, Eich C, Torreno-Pina JA, Diez-Ahedo R,
Perez-Samper G, van Zanten TS, Figdor CG, Cambi A, Garcia-Parajo
MF. Lateral mobility of individual integrin
nanoclusters orchestrates the onset for leukocyte adhesion.
Proc Natl Acad Sci U S A, 2012. 109(13):
4869-74.
47. Moulin V, Morgan ME, Eleveld-Trancikova D, Haanen JB,
Wielders E, Looman MW, Janssen RA, Figdor CG, Jansen BJ, Adema GJ.
Targeting dendritic cells with antigen via
dendritic cell-associated promoters. Cancer gene
therapy, 2012. 19(5): 303-11.
48. Wiktor-Jedrzejczak W, Dearden C, de Wreede L, van Biezen A,
Brinch L, Leblond V, Brune M, Volin L, Kazmi M, Nagler A, Schetelig
J, de Witte T, Dreger P. Hematopoietic stem cell transplantation in
T-prolymphocytic leukemia: a retrospective study from the European
Group for Blood and Marrow Transplantation and the Royal Marsden
Consortium. Leukemia : official journal of the Leukemia
Society of America, Leukemia Research Fund, U.K, 2012.
26(5): 972-6.
49. Ruutu T, van Biezen A, Hertenstein B, Henseler A, Garderet
L, Passweg J, Mohty M, Sureda A, Niederwieser D, Gratwohl A, de
Witte T. Prophylaxis and treatment of GVHD after allogeneic
haematopoietic SCT: a survey of centre strategies by the European
Group for Blood and Marrow Transplantation. Bone Marrow
Transplant, 2012. 47(11): 1459-64.
50. Aarntzen EH, de Vries IJ, Goertz JH, Beldhuis-Valkis M,
Brouwers HM, van de Rakt MW, van der Molen RG, Punt CJ, Adema GJ,
Tacken PJ, Joosten I, Jacobs JF. Humoral anti-KLH responses in cancer patients
treated with dendritic cell-based immunotherapy are dictated by
different vaccination parameters. Cancer Immunol
Immunother, 2012. 61(11): 2003-11.
51. Tel J, Smits EL, Anguille S, Joshi RN, Figdor CG, de Vries
IJ. Human plasmacytoid dendritic cells are equipped
with antigen-presenting and tumoricidal capacities.
Blood, 2012. 120(19): 3936-44.
52. Manzo C, Torreno-Pina JA, Joosten B, Reinieren-Beeren I,
Gualda EJ, Loza-Alvarez P, Figdor CG, Garcia-Parajo MF, Cambi A. The neck region of the C-type lectin DC-SIGN
regulates its surface spatiotemporal organization and virus-binding
capacity on antigen-presenting cells. J Biol
Chem, 2012. 287(46): 38946-55.
53. Tang L, Bergevoet SM, Bakker-Verweij G, Harteveld CL,
Giordano PC, Nijtmans L, de Witte T, Jansen JH, Raymakers RA, van
der Reijden BA. Human mitochondrial ATP-binding cassette
transporter ABCB10 is required for efficient red blood cell
development. British journal of haematology,
2012. 157(1): 151-4.
54. Basak GW, de Wreede LC, van Biezen A, Wiktor-Jedrzejczak W,
Halaburda K, Schmid C, Schaap N, Dazzi F, von dem Borne PA,
Petersen E, Beelen D, Abayomi A, Volin L, Buzyn A, Gurman G, Bunjes
D, Guglielmi C, Olavarria E, de Witte T. Donor lymphocyte infusions for the treatment of
chronic myeloid leukemia relapse following peripheral blood or bone
marrow stem cell transplantation. Bone Marrow
Transplant, 2012.
55. Grefte S, Vullinghs S, Kuijpers-Jagtman AM, Torensma R, Von
den Hoff JW. Matrigel, but not collagen I, maintains the
differentiation capacity of muscle derived cells in vitro.
Biomed Mater, 2012. 7(5): 055004.
56. Cruz LJ, Rueda F, Tacken P, Albericio F, Torensma R, Figdor
CG. Enhancing immunogenicity and cross-reactivity of
HIV-1 antigens by in vivo targeting to dendritic cells.
Nanomedicine (Lond), 2012. 7(10): 1591-610.
57. Aarntzen EH, Schreibelt G, Bol K, Lesterhuis WJ, Croockewit
AJ, de Wilt JH, van Rossum MM, Blokx WA, Jacobs JF, Duiveman-de
Boer T, Schuurhuis DH, Mus R, Thielemans K, de Vries IJ, Figdor CG,
Punt CJ, Adema GJ. Vaccination with mRNA-Electroporated Dendritic
Cells Induces Robust Tumor Antigen-Specific CD4+ and CD8+ T Cells
Responses in Stage III and IV Melanoma Patients. Clin
Cancer Res, 2012. 18(19): 5460-70.
58. Aarntzen EH, Srinivas M, Radu CG, Punt CJ, Boerman OC,
Figdor CG, Oyen WJ, de Vries IJ. In vivo imaging of therapy-induced anti-cancer
immune responses in humans. Cell Mol Life Sci,
2012.
59. van Gelder M, de Wreede LC, Schetelig J, van Biezen A, Volin
L, Maertens J, Robin M, Petersen E, de Witte T, Kroger N. Monosomal karyotype predicts poor survival after
allogeneic stem cell transplantation in chromosome 7 abnormal
myelodysplastic syndrome and secondary acute myeloid leukemia.
Leukemia, 2012.
60. Bonetto F, Srinivas M, Weigelin B, Cruz LJ, Heerschap A,
Friedl P, Figdor CG, de Vries IJ. A large-scale (19) F MRI-based cell migration assay
to optimize cell therapy. NMR in biomedicine,
2012. 25(9): 1095-103.
61. Karthaus N, Torensma R, Tel J. Deciphering the message broadcast by
tumor-infiltrating dendritic cells. Am J
Pathol, 2012. 181(3): 733-42.
62. Torensma R. Quantifying the efficacy of influenza vaccines.
Lancet Infect Dis, 2012. 12(9): 656.
63. Vlachos C, Schulte BM, Magiatis P, Adema GJ, Gaitanis G. Malassezia-derived indoles activate the aryl
hydrocarbon receptor and inhibit Toll-like receptor-induced
maturation in monocyte-derived dendritic cells. The
British journal of dermatology, 2012. 167(3): 496-505.
64. Zuidscherwoude M, van Spriel AB. The origin of IgE memory and plasma cells.
Cell Mol Immunol, 2012. 9(5): 373-4.
65. Gilsanz A, Sanchez-Martin L, Gutierrez-Lopez MD, Ovalle S,
Machado-Pineda Y, Reyes R, Swart GW, Figdor CG, Lafuente EM,
Cabanas C. ALCAM/CD166 adhesive function is regulated by the
tetraspanin CD9. Cell Mol Life Sci, 2012.