Publications 2010

1. Kramer M, Schulte BM, Eleveld-Trancikova D, van Hout-Kuijer M, Toonen LW, Tel J, de Vries IJ, van Kuppeveld FJ, Jansen BJ, Adema GJ. Cross-talk between human dendritic cell subsets influences expression of RNA sensors and inhibits picornavirus infection. J Innate Immun, 2010. 2(4): 360-70.

2. Spanholtz J, Tordoir M, Eissens D, Preijers F, van der Meer A, Joosten I, Schaap N, de Witte TM, Dolstra H. High log-scale expansion of functional human natural killer cells from umbilical cord blood CD34-positive cells for adoptive cancer immunotherapy. PLoS One, 2010. 5(2): e9221.

3. Di J, Yigit R, Figdor CG, Duiveman-de Boer T, Massuger LFAG, Torensma R. Expression Compilation of Several Putative Cancer Stem Cell Markers by Primary Ovarian Carcinoma. J Canc Ther, 2010. 1: 165-73.

4. Shekhar S, Klaver A, Figdor CG, Subramaniam V, Kanger JS. Spatially resolved local intracellular chemical sensing using magnetic particles. Sensors and Actuators B: Chemical, 2010. 148(2): 531-8.

5. te Riet J, Smit T, Coenen MJJ, Gerritsen JW, Cambi A, Elemans JAAW, Speller S, Figdor CG. AFM topography and friction studies of hydrogen-bonded bilayers of functionalized alkanethiols. Soft Matter, 2010. 6(15): 3450-4.

6. Jansen BJ, Gilissen C, Roelofs H, Schaap-Oziemlak A, Veltman JA, Raymakers RA, Jansen JH, Kogler G, Figdor CG, Torensma R, Adema GJ. Functional differences between mesenchymal stem cell populations are reflected by their transcriptome. Stem Cells Dev, 2010. 19(4): 481-90.

7. van Zanten TS, Cambi A, Garcia-Parajo MF. A nanometer scale optical view on the compartmentalization of cell membranes. Biochim Biophys Acta, 2010. 1798(4): 777-87.

8. Van der Reijden BA, Massop M, Simons A, de Witte T, Breuning M, Jansen JH. The NDE1 gene is disrupted by the inv(16) in 90% of cases with CBFB-MYH11-positive acute myeloid leukemia. Leukemia, 2010. 24(4): 857-9.

9. Buschow SI, Lasonder E, van Deutekom HW, Oud MM, Beltrame L, Huynen MA, de Vries IJ, Figdor CG, Cavalieri D. Dominant processes during human dendritic cell maturation revealed by integration of proteome and transcriptome at the pathway level. J Proteome Res, 2010. 9(4): 1727-37.

10. Tel J, Lambeck AJ, Cruz LJ, Tacken PJ, de Vries IJ, Figdor CG. Human plasmacytoid dendritic cells phagocytose, process, and present exogenous particulate antigen. J Immunol, 2010. 184(8): 4276-83.

11. Rizzetto L, Kuka M, De Filippo C, Cambi A, Netea MG, Beltrame L, Napolitani G, Torcia MG, D'Oro U, Cavalieri D. Differential IL-17 production and mannan recognition contribute to fungal pathogenicity and commensalism. J Immunol, 2010. 184(8): 4258-68.

12. Fransen JH, Vlag JV, Ruben J, Adema GJ, Berden JH, Hilbrands LB. The role of dendritic cells in the pathogenesis of systemic lupus erythematosus. Arthritis Res Ther, 2010. 12(2): 207.

13. Grefte S, Kuijpers-Jagtman AM, Torensma R, Von den Hoff JW. A Model for Muscle Regeneration around Fibrotic Lesions in Recurrent Strain Injuries. Med Sci Sports Exerc, 2010. 42(4): 813-9.

14. Koenecke C, Hertenstein B, Schetelig J, van Biezen A, Dammann E, Gratwohl A, Ganser A, Schleuning M, Bornhauser M, Jacobsen N, Kroger N, Niederwieser D, de Witte T, Ruutu T. Solid Organ Transplantation After Allogeneic Hematopoietic Stem Cell Transplantation: A Retrospective, Multicenter Study of the EBMT. Am J Transplant, 2010. 10(8): 1897-906.

15. ter Huurne M, Figdor CG, Torensma R. Hematopoietic stem cells are coordinated by the molecular cues of the endosteal niche. Stem Cells Dev, 2010. 19(8): 1131-41.

16. Holle N, de Witte T, Mandigers C, Schaap N, Raymakers R. Thalidomide and lenalidomide in primary myelofibrosis. Neth J Med, 2010. 68(1): 293-8.

17. Nikoloski G, Langemeijer SM, Kuiper RP, Knops R, Massop M, Tonnissen ER, van der Heijden A, Scheele TN, Vandenberghe P, de Witte T, van der Reijden BA, Jansen JH. Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes. Nat Genet, 2010. 42(8): 665-7.

18. Jacobs JF, Idema AJ, Bol KF, Grotenhuis JA, de Vries IJ, Wesseling P, Adema GJ. Prognostic significance and mechanism of Treg infiltration in human brain tumors. J Neuroimmunol, 2010. 225(1-2): 195-9.

19. Srinivas M, Aarntzen EH, Bulte JW, Oyen WJ, Heerschap A, de Vries IJ, Figdor CG. Imaging of cellular therapies. Adv Drug Deliv Rev, 2010. 62(11): 1080-93.

20. van Zanten TS, Gomez J, Manzo C, Cambi A, Buceta J, Reigada R, Garcia-Parajo MF. Direct mapping of nanoscale compositional connectivity on intact cell membranes. Proc Natl Acad Sci U S A, 2010. 107(35): 15437-42.

21. Morris C, Drake M, Apperley J, Iacobelli S, van Biezen A, Bjorkstrand B, Goldschmidt H, Harousseau JL, Morgan G, de Witte T, Niederwieser D, Gahrton G. Efficacy and outcome of autologous transplantation in rare myelomas. Haematologica, 2010. 95(12): 2126-33.

22. Ansems M, Hontelez S, Karthaus N, Span PN, Adema GJ. Crosstalk and DC-SCRIPT: Expanding nuclear receptor modulation. Biochim Biophys Acta, 2010. 1806(2): 193-9.

23. Lesterhuis WJ, de Vries IJ, Schreibelt G, Schuurhuis DH, Aarntzen EH, de Boer A, Scharenborg NM, M VDR, Hesselink EJ, Figdor CG, Adema GJ, Punt CJ. Immunogenicity of Dendritic Cells Pulsed with CEA Peptide or Transfected with CEA mRNA for Vaccination of Colorectal Cancer Patients. Anticancer Res, 2010. 30(12): 5091-7.

24. Sieuwerts AM, Ansems M, Look MP, Span PN, de Weerd V, van Galen A, Foekens JA, Adema GJ, Martens JW. Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study. Breast Cancer Res, 2010. 12(6): R103.

25. van Spriel AB, Figdor CG. The role of tetraspanins in the pathogenesis of infectious diseases. Microbes Infect, 2010. 12(2): 106-12.

26. van den Berk LC, Jansen BJ, Siebers-Vermeulen KG, Roelofs H, Figdor CG, Adema GJ, Torensma R. Mesenchymal stem cells respond to TNF but do not produce TNF. J Leukoc Biol, 2010. 87(2): 283-9.

27. Schulte BM, Bakkers J, Lanke KH, Melchers WJ, Westerlaken C, Allebes W, Aanstoot HJ, Bruining GJ, Adema GJ, Van Kuppeveld FJ, Galama JM. Detection of enterovirus RNA in peripheral blood mononuclear cells of type 1 diabetic patients beyond the stage of acute infection. Viral Immunol, 2010. 23(1): 99-104.

28. Ljungman P, Bregni M, Brune M, Cornelissen J, de Witte T, Dini G, Einsele H, Gaspar HB, Gratwohl A, Passweg J, Peters C, Rocha V, Saccardi R, Schouten H, Sureda A, Tichelli A, Velardi A, Niederwieser D. Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe 2009. Bone Marrow Transplant, 2010. 45(2): 219-34.

29. van Helden SF, van den Dries K, Oud MM, Raymakers RA, Netea MG, van Leeuwen FN, Figdor CG. TLR4-mediated podosome loss discriminates gram-negative from gram-positive bacteria in their capacity to induce dendritic cell migration and maturation. J Immunol, 2010. 184(3): 1280-91.

30. Buschow SI, Figdor CG. Dendritic Cell Subsets Digested: RNA Sensing Makes the Difference!. Immunity, 2010. 32(2): 149-51.

31. Kroger N, Shimoni A, Schilling G, Schwerdtfeger R, Bornhauser M, Nagler A, Zander AR, Heinzelmann M, Brand R, Gahrton G, Morris C, Niederwieser D, de Witte T. Unrelated stem cell transplantation after reduced intensity conditioning for patients with multiple myeloma relapsing after autologous transplantation. Br J Haematol, 2010. 148(2): 323-31.

32. Ansems M, Hontelez S, Looman MW, Karthaus N, Bult P, Bonenkamp JJ, Jansen JH, Sweep FC, Span PN, Adema GJ. DC-SCRIPT: Nuclear Receptor Modulation and Prognostic Significance in Primary Breast Cancer. J Natl Cancer Inst, 2010. 102(1): 54-68.

33. Lim Z, Brand R, Martino R, van Biezen A, Finke J, Bacigalupo A, Beelen D, Devergie A, Alessandrino E, Willemze R, Ruutu T, Boogaerts M, Falda M, Jouet JP, Niederwieser D, Kroger N, Mufti GJ, De Witte TM. Allogeneic hematopoietic stem-cell transplantation for patients 50 years or older with myelodysplastic syndromes or secondary acute myeloid leukemia. J Clin Oncol, 2010. 28(3): 405-11.

34. Srinivas M, Heerschap A, Ahrens ET, Figdor CG, de Vries IJ. (19)F MRI for quantitative in vivo cell tracking. Trends Biotechnol, 2010. 28(7): 363-70.

35. Eleveld-Trancikova D, Sanecka A, van Hout-Kuijer MA, Looman MW, Hendriks IA, Jansen BJ, Adema GJ. DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation. Mol Immunol, 2010. 47(11-12): 1963-73.

36. Bakema JE, Hiemstra IH, Bakker J, de Haij S, Kok Y, Adema G, van Egmond M, Coffer PJ, van de Winkel JG, Leusen JH. c-Jun activating binding protein 1 binds to the IgA receptor and modulates protein levels of FcalphaRI and FcRgamma-chain. Eur J Immunol, 2010. 40(7): 2035-40.

37. Schreibelt G, Benitez-Ribas D, Schuurhuis D, Lambeck AJ, van Hout-Kuijer M, Schaft N, Punt CJ, Figdor CG, Adema GJ, de Vries IJ. Commonly used prophylactic vaccines as an alternative for synthetically produced TLR ligands to mature monocyte-derived dendritic cells. Blood, 2010. 116(4): 564-74.

38. Dickinson AM, Pearce KF, Norden J, O'Brien SG, Holler E, Bickeboller H, Balavarca Y, Rocha V, Kolb HJ, Hromadnikova I, Sedlacek P, Niederwieser D, Brand R, Ruutu T, Apperley J, Szydlo R, Goulmy E, Siegert W, de Witte T, Gratwohl A. Impact of genomic risk factors on outcome after hematopoietic stem cell transplantation for patients with chronic myeloid leukemia. Haematologica, 2010. 95(6): 922-7.

39. van der Voort R, Verweij V, de Witte TM, Lasonder E, Adema GJ, Dolstra H. An alternatively spliced CXCL16 isoform expressed by dendritic cells is a secreted chemoattractant for CXCR6+ cells. J Leukoc Biol, 2010. 87(6): 1029-39.

40. Schaap-Oziemlak AM, Raymakers RA, Bergevoet SM, Gilissen C, Jansen BJ, Adema GJ, Kogler G, le Sage C, Agami R, van der Reijden BA, Jansen JH. MicroRNA hsa-miR-135b regulates mineralization in osteogenic differentiation of human unrestricted somatic stem cells. Stem Cells Dev, 2010. 19(6): 877-85.

41. Cruz LJ, Tacken PJ, Fokkink R, Joosten B, Stuart MC, Albericio F, Torensma R, Figdor CG. Targeted PLGA nano- but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro. J Control Release, 2010. 144(2): 118-26.

42. Hegmans JP, Veltman JD, Lambers ME, de Vries IJ, Figdor CG, Hendriks RW, Hoogsteden HC, Lambrecht BN, Aerts JG. Consolidative dendritic cell-based immunotherapy elicits cytotoxicity against malignant mesothelioma. Am J Respir Crit Care Med, 2010. 181(12): 1383-90.

43. Chalandon Y, Passweg JR, Schmid C, Olavarria E, Dazzi F, Simula MP, Ljungman P, Schattenberg A, de Witte T, Lenhoff S, Jacobs P, Volin L, Iacobelli S, Finke J, Niederwieser D, Guglielmi C. Outcome of patients developing GVHD after DLI given to treat CML relapse: a study by the Chronic Leukemia Working Party of the EBMT. Bone Marrow Transplant, 2010. 45(3): 558-64.

44. Levenga H, Schaap N, Maas F, Esendam B, Fredrix H, Greupink-Draaisma A, de Witte T, Dolstra H, Raymakers R. Partial T cell-depleted allogeneic stem cell transplantation following reduced-intensity conditioning creates a platform for immunotherapy with donor lymphocyte infusion and recipient dendritic cell vaccination in multiple myeloma. Biol Blood Marrow Transplant, 2010. 16(3): 320-32.

45. Figdor CG, van Spriel AB. Fungal pattern-recognition receptors and tetraspanins: partners on antigen-presenting cells. Trends Immunol, 2010. 31(3): 91-6.

46. Schulte BM, Kramer M, Ansems M, Lanke KH, van Doremalen N, Piganelli JD, Bottino R, Trucco M, Galama JM, Adema GJ, van Kuppeveld FJ. Phagocytosis of enterovirus-infected pancreatic beta-cells triggers innate immune responses in human dendritic cells. Diabetes, 2010. 59(5): 1182-91.

47. Yigit R, Massuger LF, Figdor CG, Torensma R. Ovarian cancer creates a suppressive microenvironment to escape immune elimination. Gynecol Oncol, 2010. 117(2): 366-72.

48. Rops AL, Figdor CG, van der Schaaf A, Tamboer WP, Bakker MA, Berden JH, Dijkman HB, Steenbergen EJ, van der Vlag J, van Spriel AB. The tetraspanin CD37 protects against glomerular IgA deposition and renal pathology. Am J Pathol, 2010. 176(5): 2188-97.

49. Amadori S, Suciu S, Selleslag D, Stasi R, Alimena G, Baila L, Rizzoli V, Borlenghi E, Gaidano G, Magro D, Torelli G, Muus P, Venditti A, Cacciola E, Lauria F, Vignetti M, de Witte T. Randomized trial of two schedules of low-dose gemtuzumab ozogamicin as induction monotherapy for newly diagnosed acute myeloid leukaemia in older patients not considered candidates for intensive chemotherapy. A phase II study of the EORTC and GIMEMA leukaemia groups (AML-19). Br J Haematol, 2010. 149(3): 376-82.

50. Cuijpers ML, Raymakers RA, Mackenzie MA, de Witte TJ, Swinkels DW. Recent advances in the understanding of iron overload in sideroblastic myelodysplastic syndrome. Br J Haematol, 2010. 149(3): 322-33.

51. te Riet J, Smit T, Gerritsen JW, Cambi A, Elemans JA, Figdor CG, Speller S. Molecular friction as a tool to identify functionalized alkanethiols. Langmuir, 2010. 26(9): 6357-66.

52. Verstappen J, Katsaros C, Torensma R, Von den Hoff JW. Bone marrow-derived cells in palatal wound healing. Oral Dis, 2010. 16(8): 788-94.

53. Cavalieri D, Rivero D, Beltrame L, Buschow SI, Calura E, Rizzetto L, Gessani S, Gauzzi MC, Reith W, Baur A, Bonaiuti R, Brandizi M, De Filippo C, D'Oro U, Draghici S, Dunand-Sauthier I, Gatti E, Granucci F, Gundel M, Kramer M, Kuka M, Lanyi A, Melief CJ, van Montfoort N, Ostuni R, Pierre P, Popovici R, Rajnavolgyi E, Schierer S, Schuler G, Soumelis V, Splendiani A, Stefanini I, Torcia MG, Zanoni I, Zollinger R, Figdor CG, Austyn JM. DC-ATLAS, a Systems Biology Resource to Dissect Receptor Specific Signal Transduction in Dendritic Cells. Immunome Res, 2010. 6(1): 10.

54. Hobo W, Maas F, Adisty N, de Witte T, Schaap N, van der Voort R, Dolstra H. siRNA silencing of PD-L1 and PD-L2 on dendritic cells augments expansion and function of minor histocompatibility antigen-specific CD8+ T cells. Blood, 2010. 116(22): 4501-11.

55. Schreibelt G, Tel J, Sliepen KH, Benitez-Ribas D, Figdor CG, Adema GJ, de Vries IJ. Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy. Cancer Immunol Immunother, 2010. 59(10): 1573-82.

56. Michallet M, Sobh M, Milligan D, Morisset S, Niederwieser D, Koza V, Ruutu T, Russell NH, Verdonck L, Dhedin N, Vitek A, Boogaerts M, Vindelov L, Finke J, Dubois V, van Biezen A, Brand R, de Witte T, Dreger P. The impact of HLA matching on long-term transplant outcome after allogeneic hematopoietic stem cell transplantation for CLL: a retrospective study from the EBMT registry. Leukemia, 2010. 24(10): 1725-31.

57. de Witte T, Hagemeijer A, Suciu S, Belhabri A, Delforge M, Kobbe G, Selleslag D, Schouten HC, Ferrant A, Biersack H, Amadori S, Muus P, Jansen JH, Hellstrom-Lindberg E, Kovacsovics T, Wijermans P, Ossenkoppele G, Gratwohl A, Marie JP, Willemze R. Value of allogeneic versus autologous stem cell transplantation and chemotherapy in patients with myelodysplastic syndromes and secondary acute myeloid leukemia. Final results of a prospective randomized European Intergroup Trial. Haematologica, 2010. 95(10): 1754-61.

58. Jacobs JF, Punt CJ, Lesterhuis WJ, Sutmuller RP, Brouwer HM, Scharenborg NM, Klasen IS, Hilbrands LB, Figdor CG, de Vries IJ, Adema GJ. Dendritic cell vaccination in combination with anti-CD25 monoclonal antibody treatment: a phase I/II study in metastatic melanoma patients. Clin Cancer Res, 2010. 16(20): 5067-78.

59. Lesterhuis WJ, de Vries IJ, Aarntzen EA, de Boer A, Scharenborg NM, van de Rakt M, van Spronsen DJ, Preijers FW, Figdor CG, Adema GJ, Punt CJ. A pilot study on the immunogenicity of dendritic cell vaccination during adjuvant oxaliplatin/capecitabine chemotherapy in colon cancer patients. Br J Cancer, 2010. 103(9): 1415-21.

60. Gorin NC, Labopin M, Reiffers J, Milpied N, Blaise D, Witz F, de Witte T, Meloni G, Attal M, Bernal T, Rocha V. Higher incidence of relapse in patients with acute myelocytic leukemia infused with higher doses of CD34+ cells from leukapheresis products autografted during the first remission. Blood, 2010. 116(17): 3157-62.

61. Srinivas M, Cruz LJ, Bonetto F, Heerschap A, Figdor CG, de Vries IJ. Customizable, multi-functional fluorocarbon nanoparticles for quantitative in vivo imaging using 19F MRI and optical imaging. Biomaterials, 2010. 31(27): 7070-7.

62. Grefte S, Kuijpers-Jagtman AM, Torensma R, Von den Hoff JW. Skeletal muscle fibrosis: the effect of stromal-derived factor-1-loaded collagen scaffolds. Regen Med, 2010. 5(5): 737-47.

63. Labar B, Suciu S, Willemze R, Muus P, Marie JP, Fillet G, Berneman Z, Jaksic B, Feremans W, Bron D, Sinnige H, Mistrik M, Vreugdenhil G, De Bock R, Nemet D, Gilotay C, Amadori S, de Witte T. Dexamethasone compared to prednisolone for adults with acute lymphoblastic leukemia or lymphoblastic lymphoma: final results of the ALL-4 randomized, phase III trial of the EORTC Leukemia Group. Haematologica, 2010. 95(9): 1489-95.

64. Tang L, Bergevoet SM, Gilissen C, de Witte T, Jansen JH, van der Reijden BA, Raymakers RA. Hematopoietic stem cells exhibit a specific ABC transporter gene expression profile clearly distinct from other stem cells. BMC Pharmacol, 2010. 10(1): 12.

65. Gartlan KH, Belz GT, Tarrant JM, Minigo G, Katsara M, Sheng KC, Sofi M, van Spriel AB, Apostolopoulos V, Plebanski M, Robb L, Wright MD. A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity. J Immunol, 2010. 185(6): 3158-66.