Publications 2006

1. Tacken PJ, Torensma R, Figdor CG. Targeting antigens to dendritic cells in vivo. Immunobiology, 2006. 211(6-8): 599-608.

2. van Lieshout AW, van der Voort R, le Blanc LM, Roelofs MF, Schreurs BW, van Riel PL, Adema GJ, Radstake TR. Novel insights in the regulation of CCL18 secretion by monocytes and dendritic cells via cytokines, toll-like receptors and rheumatoid synovial fluid. BMC Immunol, 2006. 7: 23.

3. Kramer M, Joosten LA, Figdor CG, Van den Berg WB, Radstake TRDJ, Adema GJ. Closing in on Toll-like receptors and NOD-LRR proteins in inflammatori disorders.. Future Rheumatology, 2006. 1(4): 465-79.

4. Jacobs H, Pereira C, Tacken P, de Vries J, Punt C, Adema G, Figdor C. 2006. Ex-vivo generated DC for clinical trials versus in vivo targeting to DC: critical issues. In DC in the pathogenesis and immunity of HIV infection.

5. Barentsz JO, Verdijk P, de Vries IJM, Lesterhuis WJ, Scheenen TWJ, Boerman OC, Oyen WJG, Adema GJ, van Krieken JHJM, Bulte J, Punt CJA, Heerschap A, Figdor CG. CMR 2005: 9.07: In vivo MR tracking of magnetically labeled dendritic cells: first clinical experience.. Contrast Media & Molecular Imaging, 2006. 1(2): 79.

6. Kramer M, Netea MG, de Jong DJ, Kullberg BJ, Adema GJ. Impaired dendritic cell function in Crohn's disease patients with NOD2 3020insC mutation. J Leukoc Biol, 2006. 79(4): 860-6.

7. Grauer O, Poschl P, Lohmeier A, Adema GJ, Bogdahn U. Toll-like receptor triggered dendritic cell maturation and IL-12 secretion are necessary to overcome T-cell inhibition by glioma-associated TGF-beta2. J Neurooncol, 2006. 82(2): 151-61.

8. le Blanc LM, van Lieshout AW, Adema GJ, van Riel PL, Verbeek MM, Radstake TR. CXCL16 is elevated in the cerebrospinal fluid versus serum and in inflammatory conditions with suspected and proved central nervous system involvement. Neurosci Lett, 2006. 397(1-2): 145-8.

9. Zimmerman AW, Joosten B, Torensma R, Parnes JR, van Leeuwen FN, Figdor CG. Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells. Blood, 2006. 107(8): 3212-20.

10. Gijzen K, Cambi A, Torensma R, Figdor CG. C-type lectins on dendritic cells and their interaction with pathogen-derived and endogenous glycoconjugates. Curr Protein Pept Sci, 2006. 7(4): 283-94.

11. Sutmuller RP, Morgan ME, Netea MG, Grauer O, Adema GJ. Toll-like receptors on regulatory T cells: expanding immune regulation. Trends Immunol, 2006. 27(8): 387-93.

12. van Helden SF, Krooshoop DJ, Broers KC, Raymakers RA, Figdor CG, van Leeuwen FN. A critical role for prostaglandin E2 in podosome dissolution and induction of high-speed migration during dendritic cell maturation. J Immunol, 2006. 177(3): 1567-74.

13. Sutmuller RP, den Brok MH, Kramer M, Bennink EJ, Toonen LW, Kullberg BJ, Joosten LA, Akira S, Netea MG, Adema GJ. Toll-like receptor 2 controls expansion and function of regulatory T cells. J Clin Invest, 2006. 116(2): 485-94.

14. Dakappagari N, Maruyama T, Renshaw M, Tacken P, Figdor C, Torensma R, Wild MA, Wu D, Bowdish K, Kretz-Rommel A. Internalizing antibodies to the C-type lectins, L-SIGN and DC-SIGN, inhibit viral glycoprotein binding and deliver antigen to human dendritic cells for the induction of T cell responses. J Immunol, 2006. 176(1): 426-40.

15. Triantis V, Trancikova DE, Looman MW, Hartgers FC, Janssen RA, Adema GJ. Identification and characterization of DC-SCRIPT, a novel dendritic cell-expressed member of the zinc finger family of transcriptional regulators. J Immunol, 2006. 176(2): 1081-9.

16. Clark K, Langeslag M, van Leeuwen B, Ran L, Ryazanov AG, Figdor CG, Moolenaar WH, Jalink K, van Leeuwen FN. TRPM7, a novel regulator of actomyosin contractility and cell adhesion. Embo J, 2006. 25(2): 290-301.

17. Beurden HE, Snoek PA, Hoff JW, Torensma R, Maltha JC, Kuijpers-Jagtman AM. In vitro migration and adhesion of fibroblasts from different phases of palatal wound healing. Wound Repair Regen, 2006. 14(1): 66-71.

18. Benitez-Ribas D, Adema GJ, Winkels G, Klasen IS, Punt CJ, Figdor CG, de Vries IJ. Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4+ T cells after Fc gamma RII-mediated uptake. J Exp Med, 2006. 203(7): 1629-35.

19. den Brok MH, Sutmuller RP, Nierkens S, Bennink EJ, Toonen LW, Figdor CG, Ruers TJ, Adema GJ. Synergy between in situ cryoablation and TLR9 stimulation results in a highly effective in vivo dendritic cell vaccine. Cancer Res, 2006. 66(14): 7285-92.

20. Lesterhuis WJ, de Vries IJ, Schuurhuis DH, Boullart AC, Jacobs JF, de Boer AJ, Scharenborg NM, Brouwer HM, van de Rakt MW, Figdor CG, Ruers TJ, Adema GJ, Punt CJ. Vaccination of colorectal cancer patients with CEA-loaded dendritic cells: antigen-specific T cell responses in DTH skin tests. Ann Oncol, 2006. 17(6): 974-80.

21. Netea MG, Gow NA, Munro CA, Bates S, Collins C, Ferwerda G, Hobson RP, Bertram G, Hughes HB, Jansen T, Jacobs L, Buurman ET, Gijzen K, Williams DL, Torensma R, McKinnon A, MacCallum DM, Odds FC, Van der Meer JW, Brown AJ, Kullberg BJ. Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors. J Clin Invest, 2006. 116(6): 1642-50.

22. Laverman P, de Vries IJ, Scharenborg NM, de Boer A, Broekema M, Oyen WJ, Figdor CG, Adema GJ, Boerman OC. Development of 111In-labeled tumor-associated antigen peptides for monitoring dendritic-cell-based vaccination. Nucl Med Biol, 2006. 33(4): 453-8.

23. Triantis V, Moulin V, Looman MW, Hartgers FC, Janssen RA, Adema GJ. Molecular characterization of the murine homologue of the DC-derived protein DC-SCRIPT. J Leukoc Biol, 2006. 79(5): 1083-91.

24. Emmer PM, van der Vlag J, Adema GJ, Hilbrands LB. Dendritic cells activated by lipopolysaccharide after dexamethasone treatment induce donor-specific allograft hyporesponsiveness. Transplantation, 2006. 81(10): 1451-9.

25. Cambi A, Joosten B, Koopman M, de Lange F, Beeren I, Torensma R, Fransen JA, Garcia-Parajo M, van Leeuwen FN, Figdor CG. Organization of the integrin LFA-1 in nanoclusters regulates its activity. Mol Biol Cell, 2006. 17(10): 4270-81.

26. den Brok MH, Sutmuller RP, Nierkens S, Bennink EJ, Frielink C, Toonen LW, Boerman OC, Figdor CG, Ruers TJ, Adema GJ. Efficient loading of dendritic cells following cryo and radiofrequency ablation in combination with immune modulation induces anti-tumour immunity. Br J Cancer, 2006. 95(7): 896-905.