Lotte de Winde
Lotte de Winde is currently working on her PhD project at the department of Tumor Immunology. Project description: The role of tetraspanin CD37 in antigen-presenting cell function. Tetraspanin proteins coordinate the spatial organization of specific immunoreceptors and signaling molecules into 'tetraspanin-enriched microdomains'. CD37 is exclusively expressed in the immune system and is involved in immune cell function, including antigen presentation, proliferation and antibody production. The aim of this PhD project is to unravel the molecular mechanisms that underlie CD37 function in immune cells in relation to the development of malignant disease.
In July 2012, Lotte de Winde graduated at the Faculty of Health, Medicine and Life Sciences at Maastricht University. She studied Molecular Life Sciences with a specialization in Oncology and Developmental Biology during her Master. During her two-year Master, she performed internships at the Tumor Immunology Departments of Maastricht and Antwerp University. In December 2012, she joined the Tumor Immunology Department in the RIMLS as a PhD student.